ap photo Virgil Abloh poses for photographers upon arrival at the Nike Celebrates The Beautiful Game event in London in 2018. Abloh, a leading fashion executive hailed as the Karl Lagerfeld of his generation, has died after a private battle with cancer.

NEW YORK — Virgil Abloh, a leading designer whose groundbreaking fusions of streetwear and high couture made him one of the most celebrated tastemakers in fashion and beyond, has died of cancer. He was 41.

Abloh’s death was announced Sunday by the luxury group LVMH (Louis Vuitton Moët Hennessy) and Abloh’s own Off-White label, which he founded in 2013. Abloh was the artistic director for Louis Vuitton’s menswear, but his ubiquitous, consumer-friendly presence in culture was wide-ranging and dynamic. Some compared him to Jeff Koons. Others hailed him as his generation’s Karl Lagerfeld.

“We are all shocked after this terrible news. Virgil was not only a genius designer, a visionary, he was also a man with a beautiful soul and great wisdom,” Bernard Arnault, chairman and chief executive of LVMH, said in a statement.

A statement from Abloh’s family on the designer’s Instagram account said Abloh was diagnosed two years ago with cardiac angiosarcoma, a rare form of cancer in which a tumor occurs in the heart.

“He chose to endure his battle privately since his diagnosis in 2019, undergoing numerous challenging treatments, all while helming several significant institutions that span fashion, art, and culture,” the statement read.

In 2018, Abloh became the first Black artistic director of men’s wear at Louis Vuitton in the French design house’s storied history. A first generation Ghanaian American whose seamstress mother taught him to sew, Abloh had no formal fashion training but had a degree in engineering and a master’s in architecture.

Abloh, who grew up in Rockford, Illinois, outside of Chicago, was often referred to as a Renaissance man in the fashion world. He moonlighted as a DJ. But in a short time, he emerged as one of fashion’s most heralded designers. Abloh called himself “a maker.” He was named one of Time magazine’s most influential people in 2018.

In 2009, Abloh met Kanye West — now called Ye — while he was working at a screen-printing store. After he and Ye interned together at the LVMH brand Fendi, Abloh was Ye’s creative director.